I was blades from RR2-5L4 (current). I haven't had too many issues. On paper Pierce should be better because it gives you higher weapon skill, and dmg is 50/50 strength and dex. I could suggest going pierce at low RR and blades at a higher RR. I can't say much until I try it.
I created a template that did not rely on the stats of a MH weapon, which means I can wield any blade or pierce I want for a MH weapon. Currently I use crafted MH and OH blades. If I were to go pierce I would really like to use the Galla vine wrapped OH. I created my template so that I can use the vine wrapped if I so choose. Possibly any OH weapon... but I don't think I got that crazy... MH for Perf has an ablative proc. All other weapons have crafted DoT. Currently running 4.2 MH and 2.5 OH. This may change.
Galla chest is a pretty big must have. You're typical S/C, D/Q, dmg add, etc /use items as well. Although this can easily change if/when the Phoenix staff implements the buff pot changes.
I believe I have heal procs on chest (Galla chest), legs and sleeves. And ablatives on the other 3 armor.